Editorial. Endothelial progenitor cells – role in atherogenesis
نویسندگان
چکیده
منابع مشابه
[The role of endothelial lipase in atherogenesis].
Endothelial lipase (EL) is synthetized by endothelial cells and its main substrates are lipoprotein phospholipids. Over expression of EL reduces high density lipoprotein (HDL) cholesterol and phospholipids, in vivo and in vitro. Inhibition of the enzyme achieves the opposite effects. The synthesis of the enzyme is regulated by interleukin 1 and tumor necrosis factor a. These inflammatory cytoki...
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Nifedipine has been shown to improve endothelial function. Recent studies have indicated that endothelial function is correlated with the number of circulating endothelial progenitor cells (EPCs), but it is unclear whether nifedipine affects the number and function of EPCs. The aims of this study were to determine the effects of nifedipine on the number and function of EPCs and to investigate t...
متن کاملRole of endothelial progenitor cells in cardiovascular pathology.
Replacement of injured endothelial cells by bone marrow derived endothelial progenitor cells (EPC's) is a new pathway of vascular repair after ischemia. Endothelial progenitor cells contribute less than 0.01% to the peripheral venous compartment of mononuclear cells. The detection of EPC's requires a demonstration of CD 34 and VEGFR-2 (vascular endothelial growth factor receptor-2) antigenic ce...
متن کاملThe role of endothelial progenitor cells in tumour vasculogenesis.
OBJECTIVE To review the biological behaviour of endothelial progenitor cells and their role and significance in tumour vasculogenesis. DATA SOURCES The data in this review were mainly from Medline and PubMed for the relevant articles in English published from March, 1997, to March, 2008. The search terms were 'endothelial progenitor cells' (EPCs) and 'neoplasm'. Articles about the biological ...
متن کاملRole of NADPH Oxidase-4 in Human Endothelial Progenitor Cells
Introduction: Endothelial progenitor cells (EPCs) display a unique ability to promote angiogenesis and restore endothelial function in injured blood vessels. NADPH oxidase 4 (NOX4)-derived hydrogen peroxide (H2O2) serves as a signaling molecule and promotes endothelial cell proliferation and migration as well as protecting against cell death. However, the role of NOX4 in EPC function is not com...
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ژورنال
عنوان ژورنال: Romanian Journal of Diabetes Nutrition and Metabolic Diseases
سال: 2012
ISSN: 2284-6417,2068-8245
DOI: 10.2478/v10255-012-0014-4